Load Cases

This module contains the load cases used for the bone spatial models. The load cases are used to implement e.g. disease states or different loading conditions for a certain time interval.

Lerebours Load Cases

This module contains the load cases for the Femur Cross Section model by Lerebours et al. (2015). The load cases are used to define disease/ loading conditions phenomenologically by either increase or decrease in resorption and formation.

class bone_models.bone_spatial_models.load_cases.lerebours_load_cases.Lerebours_Load_Case_Osteoporosis[source]

Bases: object

Load case representing osteoporosis conditions (altered PTH levels) based on the publication. Relevant to this specific model are the parameters PTH_injection, force_reduction, and moment_reduction. The latter two are zero in this case, as no mechanical unloading is considered. All other parameters are remainders from the base class.

Parameters:

start_time (int) – Start time of the load case [days]
end_time (int) – End time of the load case [days]
PTH_injection (float) – Injection rate of Parathyroid Hormone (PTH)
force_reduction (float) – Reduction factor multiplied with applied forces (1 - reduction_fraction)
moment_reduction (float) – Reduction factor multiplied with applied moments (1 - reduction_fraction)

class bone_models.bone_spatial_models.load_cases.lerebours_load_cases.Lerebours_Load_Case_Spaceflight[source]

Bases: object

Load case representing microgravity conditions (reduced loading) based on the publication. Relevant to this specific model are the parameters PTH_injection, force_reduction, and moment_reduction. The first one is zero in this case. All other parameters are remainders from the base class.

Parameters:

start_time (int) – Start time of the load case [days]
end_time (int) – End time of the load case [days]
PTH_injection (float) – Injection rate of Parathyroid Hormone (PTH)
force_reduction (float) – Reduction factor multiplied with applied forces (1 - reduction_fraction)
moment_reduction (float) – Reduction factor multiplied with applied moments (1 - reduction_fraction)